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Promising Lou Gehrig's disease drug fails trial

LONDON (Reuters) - An acne drug that had shown early promise in treating the degenerative nerve condition known as Lou Gehrig's disease actually worsens it, a study in Lancet Neurology said on Thursday.

The findings from one of the first randomized trials of the drug minocycline in patients with amyotrophic lateral sclerosis (ALS) also casts a shadow on studies planned for people with Huntington's disease, stroke and multiple sclerosis, it said.

"Our finding that minocycline has a harmful effect on patients with ALS has implications for trials of minocycline in patients with other neurological disorders," Columbia University researcher Paul Gordon and colleagues wrote. .


Sarcastic Email To Police Becomes An Internet Hit

A Sarcastic Email Sent To Police To Complain About Young Yobs Has Become A Massive Hit On The Internet. But Now Its Author Fears That Its Success Could Put Him And His Family At Risk

THE EMAIL was never meant to be seen in public.

But its outpouring of frustration to police has struck a chord with thousands after it fell into the hands of someone who posted it on the internet.

The letter, which refers to local youths in Leith, Edinburgh, as "walking abortions" and "failed medical experiments", has proved a sensation.

But the partner of the note's author now says they fear they may be identified and the targets of his sarcasm may take revenge.

The email is understood to have been sent to Lothian and Borders Police HQ by the man after he tried unsuccessfully to report the youths in his street over the phone.


Current Issue:

The world of sports has constantly demonstrated the tests of human strength, endurance and attaining personal goals.

Anabolic steroid and drug use in sports, however, has long created controversy and has also destroyed the careers of well known athletes like track star Marion Jones, who tested positive last year for the performance enhancing drug erythropoietin, or EPO.

If athletes are well aware of the repercussions — both physical and ethical — of steroid and drug abuse, why do they continue to use them?

"Most of them know that the damage is, for the most part somewhat minimal, and they know the performance improvements are significant. Most athletes, even if they think it will affect them, if they know that this is their way to the gold medal, they'll still use it," said Dan Wathen, head trainer of YSU's athletic department.


Players robbed during card game

Hanover Police are looking for two men they say robbed at gunpoint a group of adult males who were playing cards at a borough business early this morning.

Shortly after 1:30 a.m., a group of seven males were playing cards at a business in the first block of North Railroad Street that was closed to the public when two males entered the building through an unlocked front door, police said.

The robbers showed a handgun and demanded cash from the men who had met to play cards, police said.

A small amount of cash was taken from two of the men and the robbers fled on foot, police said. No one was injured.

Police did not release the name of the business.

The investigation continues and police continue to search for the robbers.

The first robber is described as a 6-foot tall white male, between 20 and 25 years of age with a thin build, short black hair, clean-shaven face and light acne.


Why Snitsky Continues To Be Pushed, Carlito Unhappy, An Update On Teddy Hart

-- Despite the crowd's apathy towards Gene Snitsky matches, Vince McMahon continues to support the bacne-ridden, yellow-toothed grappler. McMahon is a big fan of Snitsky, which explains his never-ending dominance over mid-carders and low-end wrestlers on Raw and Heat. There doesn't appear to be any end in sight in regards to Snitsky's mini-push, and thus he will continue to dominate talent in short squash matches in Goldberg-like fashion until they come up with a program for him. Although, while the Snitsky push has been going on for nine months (and counting), he still has yet to engage in a program that has lasted more than two weeks, or wrestle at a pay-per-view event for that matter.

-- Carlito is said to be unhappy with how things are going for him nowadays in WWE. The feeling backstage is that he doesn't have the attitude it takes to get a major push.


Disease made Karl Marx boil with anger

Karl Marx suffered from a skin disease that can cause severe psychological effects such as self-loathing and alienation, according to a British dermatologist.

The father of communism’s life and attitudes were shaped by hidradenitis suppurativa, said Sam Shuster in the British Journal of Dermatology. One of its symptoms is alienation – a concept that Marx, a martyr to boils and carbuncles, put into words as he wrote Das Kapital.

The condition was described as early as 1839 by a French physician, Alfred Velpeau. But, Professor Shuster says, ideas crossed the Channel less readily than wine and Marx’s true condition was never diagnosed.

Hidradenitis suppurativa is a disease of the apocrine sweat glands, found in the armpits and the groins.


Bradley Pharmaceuticals 2007 Third Quarter Results

FAIRFIELD, N.J., Nov. 8 /PRNewswire-FirstCall/ -- Bradley Pharmaceuticals, (Nachrichten) Inc. announced today that it has filed with the Securities and Exchange Commission its Quarterly Report on Form 10-Q for the quarter ended September 30, 2007.

Third Quarter of 2007 -- Launched ADOXA(R) 150mg capsules. -- Paid outstanding principal balance of $62.4 million under old credit facility on August 3, 2007 with existing cash and cash equivalents, concurrently with entering into a new credit facility and wrote-off deferred financing costs of $3.3 million related to old facility. -- On October 29, 2007, the Company entered into a definitive merger agreement with Nycomed US Inc.

Bradley reported that net sales for the quarter ended September 30, 2007 were approximately $33.6 million, a decrease of $1.6 million, or 5%, from net sales of $35.2 million for the quarter ended September 30, 2006.


 
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